We consider the implications for the ethical evaluation of research programs of two fundamental changes in the revised research ethical guideline of the Council for International Organizations of Medical Sciences. The first is the extension of scope that follows from exchanging “biomedical” for “health‐related” research, and the second is the new evaluative basis of “social value,” which implies new ethical requirements of research. We use the example of antibiotic resistance interventions to explore the need to consider the instances of what (...) we term the pragmatic risks of such interventions to evaluate the social value of certain kinds of health‐related research. These (pragmatic) risks severely threaten the social value of interventions in every area where human and social responses significantly impact on their effectiveness. Thus, the social value of health‐related research needed to demonstrate its effectiveness depends on the extent and successful management of such risks. Research designed to take into account the management of pragmatic risks also gives rise to similar types of risks, and the potential for social value in light of those risks needs to be considered in ethical reviews based on the new guidelines. We argue that, to handle this new expanded task, the international system of research ethical review addressed by the guidelines needs institutional development. (shrink)

This book explores the main stages and key concepts in the development of Kant's critical philosophy, from the early 1760s to the 1790s. Karl Ameriks provides a detailed and concise account of the main ways in which the later critical works provide a plausible defense of the conception of humanity's fundamental end that Kant turned to after reading Rousseau in the 1760s. Separate essays are devoted to each of the three Critiques, as well as to earlier notes and lectures (...) and several of Kant's later writings on history and religion. A final section devotes three chapters to post-Kantian developments in German Romanticism, accounts of tragedy up through Nietzsche, and contemporary philosophy. The theme of an elliptical path is shown to be relevant to these writers as well as to many aspects of Kant's own life and work. The topics of the book include fundamental issues in epistemology and metaphysics, with a new defense of the Amerik's 'moderate' interpretation of transcendental idealism. (shrink)

In this volume, Karl Ameriks explores 'Kantian subjects' in three senses. In Part I, he first clarifies the most distinctive features-such as freedom and autonomy-of Kant's notion of what it is for us to be a subject. Other chapters then consider related 'subjects' that are basic topics in other parts of Kant's philosophy, such as his notions of necessity and history. Part II examines the ways in which many of us, as 'late modern,' have been highly influenced by Kant's (...) philosophy and its indirect effect on our self-conception through successive generations of post-Kantians, such as Hegel and Schelling, and early Romantic writers such as Hölderlin, Schlegel, and Novalis, thus making us 'Kantian subjects' in a new historical sense. By defending the fundamentals of Kant's ethics in reaction to some of the latest scholarship in the opening chapters, Ameriks offers an extensive argument that Hölderlin expresses a valuable philosophical position that is much closer to Kant than has generally been recognized. He also argues that it was necessary for Kant's position to be supplemented by the new conception, introduced by the post-Kantians, of philosophy as fundamentally historical, and that this conception has had a growing influence on the most interesting strands of Anglophone as well as Continental philosophy. -/- . (shrink)

Was Natur für uns ist und welche Bereiche unserer Umwelt als natürlich erfahren werden, scheint sich einer prinzipiellen Bestimmung zu entziehen. Auch ist weitgehend unklar, worauf sich der verantwortliche Umgang "des" Menschen mit "der" Natur beziehen soll? Etwa auf die Erhaltung des Status quo der Natur oder auf die maßvolle Steuerung des Wandels der Natur? Ist in den gegenwärtigen umweltpolitischen und den Naturschutz betreffenden Überlegungen tatsächlich "die" Natur der Referenzrahmen verantwortlichen Handelns oder geht es uns vor allem um die Erhaltung (...) eines nützlichen Zustands für uns und nachfolgende Generationen? Die Autorinnen und Autoren des Bandes ziehen die Gewissheiten unseres theoretischen und praktischen Umgangs mit der Natur in Frage und suchen nach neuen Perspektiven. -/- Unter den Stichworten Objektive Natur (I.), Natur als Resonanzraum (II.), Natur als Ressource und Wert (III.), Natur als natürliche Umwelt (IV.), Künstliche Natur (V.), Vergesellschaftete Natur (VI.) und Verantwortete Natur (VII.) sind Beiträge der Philosophinnen Heike Baranzke und Christine Zunke sowie der Philosophen Michael Großheim, Michael Hauskeller, Kristian Köchy, Ulrich Krohs und Gregor Schiemann versammelt. Interdisziplinäre Herausforderungen zur Thematik werden in den Studien von Jörn Ahrens (Kultursoziologie), Karl-Werner Brand (Umwelt- und Nachhaltigkeitsforschung), Hans Diefenbacher (Wirtschaftswissenschaften), Thomas Fuchs (Psychiatrie), Ulrich Gebhard (Erziehungswissenschaften), Thomas Kirchhoff (Ökologie), Dörte Martens/ Nicole Bauer (Umweltpsychologie), Hartmut Rosa (Soziologie), Heinrich Spanier (Umweltschutz), Vera Tekken/ Josef Settele (Umweltforschung), Frank Uekötter (Umweltgeschichte) und Michael Wink (Biologie) deutlich herausgearbeitet. Die Beiträge der Theologen Dirk Evers und Thorsten Moos runden den Band ab. (shrink)

Diese Ausagabe macht Buchbesprechungen wieder zugänglich, die in verschiedenen Zeitschriften vom Ende des 18. Jahrhunderts verstreut erschienen sind und deswegen schwer erreichbar waren. Sie sammelt alle Dokumente, in denen von mehr oder minder bekannten Zeitgenossen Einwände gegen die Elementarphilosophie erhoben wurden, auf die Reinhold selbst in seinen Büchern antwortete. Auf diese Weise wird ein philosophischer Kontext geschildert, in dem einzelne Konstellationen deutlich werden, die sich wechselseitig widerrufen und widerlegen. Viele der zeitgenössischen Rezensionen beinhalten auBerdem einen Vergleich zwischen der Kantischen und (...) der Reinholdschen Philosophie; die vorliegende Ausgabe bringt insofern Bewertungen von Kants theoretischem Unternehmen zum Ausdruck, als dieses meistens per Kontraposition zur Elementarphilosophie, aber auch direkt beurteilt wird--Back cover. (shrink)

Reason and Rhetoric in the Philosophy of Hobbes. Quentin Skinner. Cambridge, Cambridge University Press, 1996, pp. xvi-477. ISBN 0-521-55436-5. 35.00.

Name der Zeitschrift: Zeitschrift für Religionswissenschaft Jahrgang: 25 Heft: 1 Seiten: 90-131.

Karl Britton; The Truth of Religious Propositions, Analysis, Volume 3, Issue 1-2, 1 October 1935, Pages 21–27, https://doi.org/10.1093/analys/3.1-2.21.

The paper reports an investigation on whether valid results can be achieved in analyzing the structure of datasets although a large percentage of data is missing without replacement. Two types of confirmatory factor analysis models were employed for this purpose: the missing data CFA model with an additional latent variable for representing the missing data and the semi-hierarchical CFA model that also includes the additional latent variable and reflects the hierarchical structure assumed to underlie the data. Whereas, the missing data (...) CFA model assumes that the model is equally valid for all participants, the semi-hierarchical CFA model is implicitly specified differently for subgroups of participants with and without omissions. The comparison of these models with the regular one-factor model in investigating simulated binary data revealed that the modeling of missing data prevented negative effects of missing data on model fit. The investigation of the accuracy in estimating the factor loadings yielded the best results for the semi-hierarchical CFA model. The average estimated factor loadings for items with and without omissions showed the expected equal sizes. But even this model tended to underestimate the expected values. (shrink)

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BackgroundSuicide research aims to contribute to a better understanding of suicidal behaviour and its prevention. However, there are many ethical challenges in this research field, for example, regarding consent and potential risks to participants. While studies to-date have focused on the perspective of the researchers, this study aimed to investigate the views and experiences of members of Human Research Ethics Committees (HRECs) in dealing with suicide-related study applications.MethodsThis qualitative study entailed a thematic analysis using an inductive approach. We conducted semi-structured (...) interviews with a purposive sample (N = 15) of HREC Chairs or their delegates from Australian research-intensive universities. The interview guide included questions regarding the ethical concerns and challenges in suicide-related research raised by HREC members, how they dealt with those challenges and what advice they could give to researchers.ResultsThe analysis identified four main themes: (1) HREC members’ experiences of reviewing suicide-related study applications, (2) HREC members’ perceptions of suicide, suicide research, and study participants, (3) Complexity in HREC members’ decision-making processes, and (4) HREC members’ relationships with researchers.ConclusionsReliance on ethical guidelines and dialogue with researchers are crucial in the assessment of suicide-related study applications. Both researchers and HREC members may benefit from guidance and resources on how to conduct ethically sound suicide-related studies. Developing working relationships will be likely to help HRECs to facilitate high quality, ethical suicide-related research and researchers to conduct such research. (shrink)

Research suggests that institutions affect the levels of corruption in a country. We take these arguments a step further and examine whether it is the presence of inclusive institutions and/or the credible and consistent implementation of institutions that matter, as regards corruption. We use a novel approach to theoretically conceptualise and empirically operationalise institutions along two analytically distinct dimensions: the nature of the institutions (the de jure dimension), and the extent to which they are credibly and consistently implemented over time (...) (the de facto dimension), using a panel dataset for 148 countries covering 2012 to 2018. We find that formal institutions are most effective in reducing corruption when the rules are credibly and consistently implemented. Furthermore, this effect appears to operate differently at different levels of national income. The nature of the formal institutions appears important across income levels, but particularly so at the upper middle income level, while the credible and consistent implementation of these institutions is primarily influential at upper middle income levels. We explain why this may be the case and elaborate on the policy implications. (shrink)